Association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi.
نویسندگان
چکیده
AIM To investigate the association between posterior uveal melanoma and iris freckles, iris naevi, and choroidal naevi. METHODS Cross sectional study of 65 patients with posterior uveal melanoma and 218 controls. Iris colour, iris freckles, iris naevi, and choroidal naevi were recorded for each eye of each patient. RESULTS Iris freckles were present in 40 (61.5%) patients with melanoma and 135 (61.9%) controls (p = 0.494). Iris naevi were present in four (6.2%) patients with melanoma and nine (4.1%) controls (p = 0.955). Choroidal naevi were present in 12 (18.5%) patients with melanoma and 38 (17.4%) controls (p = 0.815). CONCLUSION This study did not detect an association between posterior uveal melanoma and iris freckles, iris naevi, or choroidal naevi.
منابع مشابه
Risk Factors and Relationship of Cutaneous and Uveal Melanocytic Lesions in Monozygotic and Dizygotic Twin Pairs
BACKGROUND The similar genetic background of a pair of twins, and the similar environmental impacts to which they are exposed allow an exact and objective investigation of various constitutional and environmental factors in naevus development. As far as we are aware, this is the first published survey that simultaneously examines cutaneous and ocular pigmented lesions in an appreciable sample o...
متن کاملMultiple malignant melanomata of the uveal tract in one eye.
THE literature on malignant melanoma of the uveal tract is extensive but case reports of multiple malignant tumours of this type are infrequent. Freckles and naevi are present in approximately 50 per cent. of normal eyes and "are even more frequent and larger in eyes which also contain malignant melanoma of the uveal tract" (Hogan and Zimmerman, 1962). According to Reese (1956), when the malign...
متن کاملAssociation between choroidal pigmentation and posterior uveal melanoma in a white population.
BACKGROUND/AIMS It is well known that light skin pigmentation is a risk factor for cutaneous melanoma. The aim of this study was to investigate the analogous association between choroidal pigmentation and posterior uveal melanoma. METHODS Cross sectional study of 65 consecutive patients diagnosed with posterior uveal melanoma (melanoma group) and 218 consecutive patients referred for general ...
متن کاملSCIENTIFIC REPORT Association between choroidal pigmentation and posterior uveal melanoma in a white population
Background/aims: It is well known that light skin pigmentation is a risk factor for cutaneous melanoma. The aim of this study was to investigate the analogous association between choroidal pigmentation and posterior uveal melanoma. Methods: Cross sectional study of 65 consecutive patients diagnosed with posterior uveal melanoma (melanoma group) and 218 consecutive patients referred for general ...
متن کاملPulverulent cataract with variably associated microcornea and iris coloboma in a MAF mutation family.
AIMS To report the detailed clinical findings in a three generation pedigree with autosomal dominant cataract, microcornea, and coloboma resulting from mutation of the lens development gene, MAF. METHODS Five members of a three generation pedigree with progressive cataracts underwent detailed ophthalmic examination to characterise associated ocular phenotypic features. RESULTS The cataracts...
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ورودعنوان ژورنال:
- The British journal of ophthalmology
دوره 88 1 شماره
صفحات -
تاریخ انتشار 2004